Next-Generation Antiplatelet and Antithrombotic Strategies
Platelet activation and thrombus formation are central mechanisms in coronary artery disease and heart failure-related events. While dual antiplatelet therapy (DAPT) and anticoagulants remain the standard, bleeding risks and variable responses necessitate novel approaches. Next-generation antiplatelet drugs, including reversible P2Y12 inhibitors and protease-activated receptor antagonists, are being developed to optimize efficacy while reducing adverse effects. Similarly, direct oral anticoagulants (DOACs) continue to evolve, offering simplified dosing and superior safety compared to traditional vitamin K antagonists.
Emerging research focuses on personalized antithrombotic strategies guided by genetic testing, platelet function assays, and AI-driven risk models. Novel combination regimens and drug-eluting technologies may further refine therapy for high-risk patients. This track will provide insights into the latest advances in thrombosis management, highlighting ongoing clinical trials, real-world outcomes, and strategies for balancing ischemic protection with bleeding risk. Attendees will gain perspective on how next-generation therapies could reshape cardiovascular intervention protocols.
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